On one end, organ specific responses with organ specific autoantibodies and T cells produce tissue alteration.
Autoimmune inner ear disease (AIED) is an incendiary circumstance of the inner ear. The reason of AIED is mostly assumed to be related to either antibodies or exempt cells that induce harm to the inner ear. There is evidence that genetically controlled aspects of the immune system may increase or otherwise be associated with increased susceptibility to common hearing disorders such as menieres disease. It seems that allergies can cause or at least are associated with autoimmune inner ear disease. Observation suggests there is a genetic component as autoimmune diseases seem to cluster in families. Interestingly, this trait may show up as several different autoimmune diseases within the same family. However, this genetic predisposition alone does not cause autoimmune diseases to develop. Other factors need to be present as well in order to initiate the disease process.